Lean Performance Lab LPL

Full body vs split routine

Either works: with the same weekly sets per muscle, full body and split routines build similar muscle and strength.
Evidence Moderate Reviewed Sources2
Side by side
Full bodySplit routine
Muscle growthEqual at matched weekly volumeEqual at matched weekly volume
Sessions per week2 to 44 to 6
Session lengthLonger, more compound lifts per sessionShorter, more focused
If you miss a sessionYou still hit everything that weekA muscle group can go a full week untrained
Frequency per muscle2 to 4 times per week1 to 2 times per week
Volume per muscle per sessionLow, so quality stays highHigh, so the later sets are done tired
Best for beginnersMore practice at each liftHarder to justify early on
Best for advancedSessions get long once volume is highSplits the volume into manageable days
Which one
Full body

Pick full body if you train two or three times a week, are still learning the lifts, or have an unpredictable schedule.

Split routine

Pick a split once your weekly volume no longer fits into sensible sessions, which for most people is somewhere past the first year.

What actually decides it

Pick the routine you can keep doing week after week. Count your weekly sets per muscle, keep them between 10 and 20, and arrange them however fits your week.

Sources2